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Treatment of Patients with Neuropathy and Anti-MAG IgM M-Proteins
Ann Neurol 24:93-97, Nobile-Orazio,E.,et al, 1988
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Article Abstract
Five patients with neuropathy and IgM M-proteins that reacted with myelin- associated glycoprotein(MAG)were treated for 10 to 20 months with cytostatic agents.In 2 patients,a decrease in serum M-protein and in anti- MAG IgM levels coincided with a progressive improvement of neuropathy.No clinical improvement and no decrease of anti-MAG IgM were observed in the other patients.The close relationship between the decrease of anti-MAG M- proteins and clinical improvement in these patients supports the pathogenetic role of the M-protein in the neuropathy.
 
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anti MAG antibodies
autoantibodies
monoclonal gammopathy
neuropathy
neuropathy,peripheral,treatment
treatment of neurologic disorder

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